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Why do you think the presence of a specific type of keratin, an intermediate filament protein, in the bloodstream or lymph node is an indicator of metastasis of tumor cells?


A) Intermediate filaments are only found in tumor cells.
B) Keratin is only present if its specific cell type is also present.
C) Intermediate filament proteins cause cells to clump together.
D) None of the other answer options is correct.

E) B) and C)
F) A) and C)

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Which of the following is NOT found in the extracellular matrix of animal cells?


A) cellulose
B) elastin
C) collagen
D) laminin
E) polysaccharide

F) All of the above
G) A) and E)

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Which one of the following cytoskeletal elements is associated with supporting the movement of materials inside the cell?


A) microtubules
B) microfilaments
C) intermediate filaments
D) both microtubules and microfilaments

E) A) and C)
F) A) and B)

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Which of the following CORRECTLY lists components of extracellular matrix found in plants?


A) collagen, laminin, and elastin
B) collagen, lignin, laminin, and pectin
C) lignin, pectin, and keratin
D) cellulose, pectin, and lignin

E) A) and B)
F) All of the above

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A researcher is studying a population of cells that are shaped normally, but appear to slide past one another. This is likely the result of mutations in genes encoding:


A) components of the extracellular matrix.
B) components of cell junctions.
C) components of the cytoskeleton.
D) components of microvilli.
E) components of both the extracellular matrix and cytoskeleton.

F) C) and D)
G) A) and D)

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The basal lamina is:


A) an area found beneath all connective tissues that helps them adhere to underlying muscle.
B) a specialized form of the extracellular matrix found beneath all epithelial tissues.
C) a specialized form of the extracellular matrix found only in the skin.
D) an area found wherever two different types of tissues meet.

E) None of the above
F) All of the above

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The extracellular matrix can influence:


A) cell movement.
B) cell shape.
C) gene expression.
D) All of these choices are correct.

E) A) and D)
F) All of the above

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Which one of the following statements about connective tissue is TRUE?


A) Connective tissue is very cell dense.
B) Connective tissue lacks a strong extracellular matrix.
C) Cells composing connective tissue typically have microvilli.
D) Connective tissue cells are typically multinucleate.
E) None of the other answer options is correct.

F) A) and B)
G) A) and C)

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Which of the following could NOT be a part of the extracellular matrix made by an animal cell?


A) collagen
B) lignin
C) elastin
D) laminin

E) A) and C)
F) All of the above

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The cytoskeleton of animal cells includes:


A) microtubules, microfilaments, and intermediate filaments.
B) actin, microfilaments, and intermediate filaments.
C) actin, microtubules, and intermediate filaments.
D) tubulin, microfilaments, and intermediate filaments.
E) microtubules and microfilaments.

F) B) and D)
G) A) and E)

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Which of the following statements about intracellular transport is TRUE?


A) Kinesin and myosin move substances toward the "plus end" of microtubules and microfilaments, respectively.
B) Kinesin and myosin move substances toward the "minus end" of microtubules and microfilaments, respectively.
C) Myosin and kinesin move substances toward the "plus end" of microtubules and microfilaments, respectively.
D) Myosin and kinesin move substances toward the "minus end" of microtubules and microfilaments, respectively.

E) B) and C)
F) All of the above

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A cadherin protein can only bind to:


A) another cadherin.
B) another cadherin of a different type.
C) the extracellular domain of the same type of cadherin.
D) the extracellular matrix.

E) All of the above
F) C) and D)

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Which of the following types of cell junctions are found in skin?


A) adherens junctions
B) tight junctions
C) desmosomes
D) hemidesmosomes
E) All of these choices are correct.

F) A) and B)
G) A) and C)

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What would happen to a cell that depends on flagellar movement if it had no actin?


A) The cell would not be able to move because the cilia would also be affected.
B) The cell would not be able to move.
C) Nothing; the cell would still be able to move.
D) The cell would move by cilia and not flagella.

E) A) and B)
F) All of the above

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A cell's particular shape is largely determined by:


A) cytoskeletal protein networks in the cytoplasm.
B) a mesh of proteins and polysaccharides in the extracellular matrix.
C) cytosolic proteins that assemble into structures called cell junctions.
D) All of these choices are correct.

E) C) and D)
F) None of the above

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Which of the following is a FALSE statement about the motor proteins myosin and kinesin?


A) They both use ATP.
B) They both move cargo to the plus end of a cytoskeletal filament.
C) They both move along microtubules.
D) None these statements about myosin and kinesin is false.

E) None of the above
F) B) and D)

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Which of the following cytoskeletal elements is capable of assembling and disassembling in the cell?


A) microtubules
B) intermediate filaments
C) microfilaments
D) both microtubules and microfilaments

E) A) and D)
F) B) and C)

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Which is the CORRECT order from lesser to greater complexity for the following?


A) organs, tissues, cells
B) cells, tissues, organs
C) tissues, organs, cells
D) cells, organs, tissues

E) B) and C)
F) A) and D)

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Macrophage cells undergo a process called phagocytosis in which material is brought into a cell in the form of membrane vesicles and then transported along microtubules toward the cell center. Assuming that the centrosome is near the cell center, you can predict that these vesicles are moving to the _____ end of microtubules using the motor protein _____.


A) minus end; kinesin
B) plus end; kinesin
C) minus end; dynein
D) plus end; dynein

E) A) and B)
F) A) and C)

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A benign tumor:


A) is a mass of rapidly dividing cells.
B) has clear boundaries encapsulating it and does not invade nearby tissues.
C) rarely has life-threatening effects unless it is interfering with the function of a vital organ.
D) has defects in the regulation of cell division.

E) A) and B)
F) All of the above

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