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The genetic disease blue sclera is determined by an autosomal dominant allele. The eyes of individuals with this allele have bluish sclera. These same individuals may also suffer from fragile bones and deafness. This is an example of


A) incomplete dominance.
B) pleiotropy.
C) epistasis.
D) codominance.
E) linkage.

F) A) and B)
G) A) and E)

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A human male carrying an allele for a trait on the X chromosome is


A) heterozygous.
B) homozygous.
C) hemizygous.
D) monozygous.
E) holozygous.

F) B) and E)
G) All of the above

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In mice, short hair is dominant to long hair. If a short-haired individual is crossed with a long-haired individual and both long- and short-haired offspring result, one can conclude that


A) the short-haired individual is homozygous.
B) the short-haired individual is heterozygous.
C) the long-haired individual is homozygous.
D) the long-haired individual is heterozygous.
E) This cannot be answered without more information.

F) B) and C)
G) A) and E)

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When many genes contribute to the phenotype, variation is said to be continuous, or _______.

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If Mendel had performed experiments on cattle rather than on peas, the patterns of inheritance would not have been easily detectable, because cattle


A) reproduce asexually.
B) have small numbers of offspring.
C) do not have observable phenotypes.
D) do not have genotypes.
E) do not have autosomes.

F) C) and D)
G) C) and E)

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Recombination is most likely to occur between two loci that are _______.

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Incomplete dominance


A) results in a phenotypic ratio of 1:2:1 in a monohybrid cross.
B) is far less common than complete dominance.
C) is the same as codominance.
D) involves the distinct expression of both alleles, as in the ABO blood group system.
E) occurs only in X-linked genes.

F) None of the above
G) A) and B)

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Genes located on mitochondrial DNA are usually inherited in what fashion?


A) Randomly
B) From the mother
C) From the father
D) Evenly from both the mother and the father
E) By independent assortment

F) A) and E)
G) A) and D)

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What fraction of the offspring of the cross AaBb Γ—\times AaBb would show the dominant phenotypes for both genes?


A) 9/16
B) 3/16
C) 6/16
D) 12/16
E) 1/3

F) C) and D)
G) A) and C)

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A dihybrid cross


A) results in a genotypic ratio of 2:1.
B) involves genes located on the sex chromosomes.
C) results in offspring of lower quality than that of the parents.
D) results in two different phenotypes in the F2 generation.
E) is a cross between identical double heterozygotes.

F) A) and D)
G) All of the above

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A linkage group corresponds to


A) a group of genes on different chromosomes.
B) the linear order of centromeres on a chromosome.
C) the length of a chromosome.
D) a group of genes on the same chromosome.
E) None of the above

F) A) and B)
G) A) and E)

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Draw a pedigree for three generations in which the grandfather has red-green color blindness and his daughter is a carrier. This daughter has four sons. Predict how many of the sons will be color-blind.

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To draw the pedigree, we can represent t...

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Quantitative variation is the result of the interaction of _______ and _______.

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When a given trait is the result of multigene action, one of the genes may mask the expression of one or all other genes. This phenomenon is termed


A) epistasis.
B) epigenesis.
C) dominance.
D) incomplete dominance.
E) None of the above

F) C) and E)
G) A) and E)

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In the garden peas used in Mendel's experiments, the spherical seed character (SS) is completely dominant over the wrinkled seed character (ss) . If the characters for height were incompletely dominant, such that TT was tall, Tt was intermediate, and tt was short, what would have resulted from crossing a spherical-seeded, short (SStt) plant to a wrinkled-seeded, tall (ssTT) plant?


A) One-half would be smooth-seeded and intermediate height; one-half would be smooth-seeded and tall.
B) All the progeny would be smooth-seeded and tall.
C) All the progeny would be smooth-seeded and short.
D) All the progeny would be smooth-seeded and intermediate in height.
E) This cannot be answered without more information.

F) A) and B)
G) A) and C)

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In the F2 generation of a dihybrid cross


A) four phenotypes appear in the ratio 9:3:3:1 if the loci are linked.
B) four phenotypes appear in the ratio 9:3:3:1 if the loci are unlinked.
C) two phenotypes appear in the ratio 3:1 if the loci are unlinked.
D) three phenotypes appear in the ratio 1:2:1 if the loci are unlinked.
E) two phenotypes appear in the ratio 1:1 whether or not the loci are linked.

F) A) and E)
G) A) and B)

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What is the probability that a cross between a true-breeding pea plant with spherical seeds and a true-breeding pea plant with wrinkled seeds will produce F1 progeny with spherical seeds?


A) 1/2
B) 1/4
C) 0
D) 1/8
E) 1

F) B) and E)
G) B) and C)

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A(n) _______ trait is one that can be passed from one generation to another.

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Classical albinism results from a recessive allele. Which of the following is the expected ratio for the progeny when a normally pigmented male with an albino father has children with an albino woman?


A) 3/4 normal; 1/4 albino
B) 3/4 albino; 1/4 normal
C) 1/2 normal; 1/2 albino
D) All normal
E) All albino

F) B) and E)
G) A) and D)

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In guppies, fan tail is dominant to flesh tail, and rainbow color is dominant to pink. F1 female guppies are crossed with flesh-tailed, pink-colored males, and the following progeny are observed: 401 fan-tailed, pink-colored; 399 flesh-tailed, rainbow-colored; 98 flesh-tailed, pink-colored; and 102 fan-tailed, rainbow-colored guppies. Assuming that the F1 female guppies have both dominant alleles on one chromosome, the map distance between these two genes is


A) 80 cM.
B) 25 cM.
C) 0.8 cM.
D) 20 cM.
E) None of the above

F) A) and B)
G) All of the above

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